IGVF U24 Program: This announcement for universities or research institutions has been made by the National Human Genome Research Institute (NHGRI). They are going to launch a new funding program (NOFO), which aims to establish an “IGVF Data and Coordinating Center (DACC)”. This center will be a key part of the IGVF consortium and will do several things:
IGVF U24 Program: Create a data portal that is accessible to everyone. Create a complete catalog of information on all genetic variants (genetic changes) whose effects have been measured or estimated. Seek advice from the scientific community to improve this catalog. Organize meetings and activities of the IGVF consortium. Explore opportunities to work together with other research programs. This announcement is made in advance so that researchers and institutions can prepare in time and develop a good application. This funding notice is likely to be issued in 2025 and the deadline for submitting applications will also be in 2025. This program will operate under a research grant code called “U24”.
Apply through: morriss2@mail.nih.gov
IGVF U24 Program: Eligibility
Eligible applicants
Education
🎓 Private Institutions of Higher Education
Colleges or universities that are privately run, meaning they are owned by a private entity or organization rather than the government.
🏫 Independent School Districts
School districts or school systems that are locally autonomous and set their own educational policies. They are usually made up of a group of schools.
🏛️ Public and State Institutions of Higher Education
Universities or colleges that are run by the government or state, such as public universities.
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| 🏷️ Category | 📋 Details |
|---|---|
| 🏛️ Program Name | IGVF Data and Coordinating Center (DACC) – U24 Grant |
| 🏢 Announced By | National Human Genome Research Institute (NHGRI) |
| 🎯 Key Objectives | Data portal creation, variant cataloging, community feedback, coordination |
| 🚀 Expected Launch | 2025 |
| 📅 Application Deadline | 2025 |
| 🧑🎓 Eligible Applicants | Universities, school districts, state/county/tribal governments, nonprofits, businesses |
| 📧 Contact Email | morriss2@mail.nih.gov |
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Government
🏛️ State Governments
Each state in the United States has its own government, such as California, Texas, New York, etc., which conducts legislative and administrative affairs in their state.
🏙️ County Governments
Governments of administrative areas (counties) within a state, which provide services at the local level such as police, fire brigade, health, education, etc.
🪶 Federally Recognized Native American Tribal Governments
Tribal governments that are legally recognized by the US federal government. These tribes have autonomous status and conduct their own internal affairs.
🏘️ Public and Indian Housing Authorities
Agencies that provide affordable or subsidized housing to the public, especially for low-income individuals or Native American tribes.
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Business
🧾 Small Businesses
Businesses that operate on a limited scale, such as small companies, shops, or service providers. Their number of employees and revenue are below certain thresholds (which may vary from country to country).
🏢 For-Profit Organizations Other Than Small Businesses
Large businesses or companies that operate for profit but do not meet the definition of a small business in terms of size, such as large companies, corporations, or industries.
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Nonprofit
🌀 Other Native American Tribal Organizations
Tribal organizations that represent Native American tribes but are not necessarily recognized as full “tribes” by the federal government. These organizations work to promote community service, health, education, or culture.
🤝 Nonprofits (Non-Higher Education) with 501(c)(3)
Nonprofit organizations that are tax-exempt under section 501(c)(3) of the U.S. income tax laws, but are not educational institutions such as universities or colleges.
Examples: Charities, foundations, social service organizations, community centers, etc.
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contact information
morriss2@mail.nih.gov
morriss2@mail.nih.gov
What is the IGVF Data and Coordinating Center (DACC) and how does it support the IGVF U24 Program?
The IGVF Data and Coordinating Center (DACC) is a central hub for managing and integrating data generated by the IGVF U24 Program. It facilitates collaboration among funded research teams and ensures proper data storage, access, and sharing to support functional genomics research under the Genetic Variant Catalog Grant initiatives.
Who is eligible to apply for the NHGRI Funding Opportunity 2025 under the U24 mechanism?
The NHGRI Funding Opportunity 2025 under the U24 Research Grant Eligibility criteria is open to domestic and foreign institutions, including universities, non-profit organizations, and for-profit companies with the capacity to conduct large-scale genomic data coordination. Applicants must demonstrate expertise in managing data repositories or genomic analysis platforms relevant to the IGVF U24 Program.
What are the main goals of the Genetic Variant Catalog Grant under the IGVF initiative?
The Genetic Variant Catalog Grant aims to identify and catalog variants that impact gene function and regulation. Through the IGVF Data and Coordinating Center (DACC), data from multiple sources are integrated to develop a comprehensive reference for genetic variant interpretation, a key focus of the IGVF U24 Program.
How does the U24 grant mechanism differ from other NIH funding types?
The U24 Research Grant is a cooperative agreement that involves substantial NIH programmatic involvement. In the context of the IGVF U24 Program, this mechanism ensures that grantees coordinate efforts with NHGRI and the IGVF Data and Coordinating Center (DACC) to support data harmonization, sharing, and collaborative research outlined in the NHGRI Funding Opportunity 2025.
How can researchers participate in the IGVF U24 Program through the 2025 NHGRI funding round?
To participate in the IGVF U24 Program, researchers should carefully review the NHGRI Funding Opportunity 2025 announcement, ensuring they meet the U24 Research Grant Eligibility criteria. Proposals should align with the program’s mission to support variant-to-function studies and contribute data to the Genetic Variant Catalog Grant coordinated through the IGVF DACC.